| http://www.w3.org/ns/prov#value | - Pro-inflammatory cytokines such as IL-1??, TNF??, and IL-6 have been shown to modulate extracellular matrix turnover, to accelerate the degradation of cartilage, and to induce apoptosis in chondrocytes [3,4].Besides promoting imbalance between excessive cartilage destruction and cartilage repair processes, IL-1?? has been a potent inducer of reactive oxygen species, including nitric oxide and infl
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