| http://www.w3.org/ns/prov#value | - This intracellular enzyme is activated by external receptor mediated signals that mobilise calcium or phosphorylate mitogen and/or stress activated kinase pathways, in particular the ERK, p38, and JNK. In chronic inflammatory conditions, the proinflammatory cytokines, including TNF, are important activators of this enzyme and blockade of these cytokines effectively limits the flux of arachidonic a
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