| http://www.w3.org/ns/prov#value | - The major weakness of this model is that intrarectal injection poses a significant technical challenge, and quantification of carcinogens instilled intrarectally is difficult.Chemically induced gene mutationsThere are a number of pathways leading to colon cancer in humans, including the sporadic and FAP-associated adenoma???carcinoma sequence, hereditary non-polyposis colorectal cancer and colitis
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