| http://www.w3.org/ns/prov#value | - The most common adverse effects of metformin are gastrointestinal discomfort and diarrhea, which can be minimized by slow titration of the dose and administration with food.15 When used alone, metformin typically does not cause hypoglycemia and is usually weight neutral or causes modest weight loss.9,10 Given the low risk of hypoglycemia, metformin has an important role in elderly patients with di
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