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  • This more than doubles the relaxivity pH response, ??r1, of our agent from just 51% for the original low molecular weight chelate to 122% for the dendrimer.Keywords: dendrimers, imaging agents, lanthanide complexes, MRI contrast agentsIntroductionDiseases, such as kidney disorders and cancer, often result in a significant reduction in the extracelluar pH of these tissues.[1???3] Thus, imaging tiss
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