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  • The limitations of this approach are increasingly evident, as clinicopathologic studies demonstrate clinical and anatomic overlap between diseases.4,5,7,9 While PiB directly measures molecular pathology, neuroimaging techniques such as MRI and FDG-PET measure the secondary effects of disease on brain structure and function, and may ultimately fail to predict the underlying histopathology when neur
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  • pubmedcentralcanada.ca