| http://www.w3.org/ns/prov#value | - The ?? and ?? chains are the signal transducing domains of Fc??RI. Allergen cross-linking of IgE bound to mast cells results in stimulation of Fc??RI and activation of a number of signal transduction pathways that lead to the release of a range of proinflammatory mediators and cytokines, including bronchoconstrictive and vasoactive substances, such as histamine, leukotrienes and various other cyto
|
