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  • The generation of an A. niger strain devoid of naphtho-??-pyrones will greatly facilitate the elucidation of cryptic biosynthetic pathways in this organism.Keywords: Secondary Metabolism, Aspergillus niger, Natural Products, Genomics, Naphtho-??-pyrone, PolyketidesINTRODUCTIONFungi live in complex ecosystems and must compete with other organisms such as bacteria, algae, other fungi, protozoans and
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