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  • The prefrontal cortex Intracranial self-administration studies also found that rats learn to self-administer drugs, including cocaine, into the medial prefrontal cortex, another projection region of the VTA. Although no study has systematically examined its effective zone within the prefrontal cortex, rats learn to self-administer cocaine (Goeders and Smith, 1983; Goeders et al., 1986) and NMDA re
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  • pubmedcentralcanada.ca