| http://www.w3.org/ns/prov#value | - The proinflammatory cytokines, particularly TNF??, then provoke hepatocellular injury and death by extrinsic, via TNFR1 [5] and intrinsic death pathways [6] leading to ALD. While the role of oxidative stress and macrophage activation, the two main pathophysiological processes affected in ALD, were studied independently in the past, recent studies suggest that these pathways are interconnected in A
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