| http://www.w3.org/ns/prov#value | - Rapid estrogen actions occur in the cytoplasm within minutes of estrogen exposure and are characterized by increased phosphorylation and activation of many signaling molecules including ER-??, epidermal growth factor receptor (EGFR) family members, extracellular regulated kinase (ERK) 1/2, c-Src, and phosphoinositide 3-kinase (PI3K) [27,28].
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