| http://www.w3.org/ns/prov#value | - Although some of these symptoms, such as dementia and psychosis, typically appear late in the course of the disease, other nonmotor symptoms may occur early in the disease, even before the onset of motor problems, and many continue to be common across all stages of PD. Although the anatomic, pathologic, and biochemical substrates for much of the PD symptom complex are yet to be fully characterized
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