| http://www.w3.org/ns/prov#value | - Also, pro-inflammatory cytokines, e.g. IL-1 and TNF-?? and IL-1, will inhibit fibroblast-mediated collagen gel contraction.57 Prostaglandins have been demonstrated to act as second messengers for the inhibitory effects of IL-1 and TNF-?? on contraction,58 and prostaglandins E1, E2, and I2 inhibit fibroblast-mediated collagen gel contraction.39 cAMP has been suggested to interfere with collagen gel
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