| http://www.w3.org/ns/prov#value | - A conservative amino acid substitution is an amino acid substituted by an alternative amino acid of similar charge density, hydrophilicity/hydrophobicity, size, and/or configuration (e.g., basic, Arg and Lys; aliphatic Ala, Cys, Gly, Ile, Leu, Met and Val; aromatic, Phe, Tyr, Trp, and His; hydrophilic, Glu, Gln, Asn, and Asp; hydroxyl, Ser and Thr).
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