| http://www.w3.org/ns/prov#value | - Our observation that ATP-induced MHC-II secretion was insensitive to genetic deletion of caspase-1 but sensitive to zVAD-fmk and TPCK, which are widely used pharmacological inhibitors of proteases, indicates that proteases other than caspase-1 may act either upstream or downstream of ASC/NLRP3 inflammasome assembly.
|
