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  • us types of cancer including lymphoma and leukemia (He et al., 2005; Hoffman et al., 2002; O???Donnell et al., 2005), we tested the hypothesis that the MYC/LIN28 axis plays an essential role in AML in which MYC functions as an important downstream target of MLL fusions and FLT3 through post-transcriptional regulation of maturation of some critical tumor-suppressor miRNAs.RESULTSExpression of miR-1
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  • pubmedcentralcanada.ca