| http://www.w3.org/ns/prov#value | - Due to a low degree of coupling between enzyme turnover and substrate binding, CYP2E1 has an unusually high capacity of generating free radicals, which are thought to result in lipid peroxidation, thus contributing to liver disease, including nonalcoholic steatohepatitis (NASH), which is closely associated with T2DM [57].ROS activate a number of stress-sensitive kinases, whose downstream effects m
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