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  • Disorders such as Alzheimer???s disease (AD), Parkinson???s disease (PD), Huntington???s disease (HD), ALS and prion-protein diseases all share one common feature: accumulation and aggregation of misfolded proteins20,21 (see pages 774 and 803).Mediators of cell death induced by misfolded proteins have recently been identified (Box 2).
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  • pubmedcentralcanada.ca