| http://www.w3.org/ns/prov#value | - Here we have shown that (1) L-glutamine is an essential and rate-limiting sensitizing factor that allows EAA and growth factors to activate mTOR, (2) the high affinity L-glutamine transporter SLC1A5 and the heterodimeric SLC7A5/SLC3A2 bidirectional transporter are required for amino acid transport, mTORC1 pathway activity and cell growth, and (3) L-glutamine and SLC1A5 function are required to sup
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