| http://www.w3.org/ns/prov#value | - Recent in vitro studies suggest that hyperoxic exposure leads to upregulation of platelet-derived growth factor receptors and that oxidants such as hydrogen peroxide stimulate endothelial cells and keratinocytes to release VEGF.12,13 In addition, macrophages and endothelial cells that are exposed to hyperoxia up-regulate IL-8, transforming growth factor ??, and VEGF messenger RNA.14- 16 The possib
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