| http://www.w3.org/ns/prov#value | - Because deregulated Hh signaling influences ??-catenin signaling primarily at the level of Wnt ligands, the range of potential therapeutic strategies is considerably greater than it is for colorectal and other cancers with mutational defects in APC or ??-catenin, and would likely include antibodies or other recombinant proteins that antagonize the interaction of Wnt ligands with Frizzled and LRP r
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