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  • We propose that citrullinated MBP, resulting from elevated levels of PAD 2 represents an important biochemical pathway in the pathogenesis of MS.Keywords: Multiple sclerosis, Demyelination, Citrulline, Peptidyl arginine deiminase, Apoptosis, MyelinIntroductionDemyelinating diseases, such as multiple sclerosis (MS), the major demyelinating disease of humans affects not only young adults, but also c
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  • nih.gov