| http://www.w3.org/ns/prov#value | - Mechanistically, IL-7, a type-I cytokine, may have a critical role in such a switch as levels correlates with CD4 T-cell depletion.[28], [38] IL-7 also appears to increase CD4+ T-cell surface CXCR4 density, HIV-1 production and the risk of emergence of X4-tropic strains of virus.[39] In addition, non-specific activation by cytokines, superantigens, or antigen-specific recruitment from gut microbia
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