| http://www.w3.org/ns/prov#value | - Like to Dyrk1A, ASK1 activity also contributes to the cell death in the neurodegenerative diseases, including AD and HD. The accumulation of intracellular aggregates induced cellular stress, which subsequently leads to neuronal cell death in an ASK1-dependent manner in HD (Nishitoh et al., 2002).
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