| http://www.w3.org/ns/prov#value | - are susceptible to exonucleases and endonucleases in blood and other body fluids, and (2) because of their small size (generally about 25???30 kD), aptamers are rapidly cleared from circulation by the kidneys and other major organs, thereby drastically reducing their pharmacokinetic lifetime and therapeutic potential [61].Several different biochemical approaches have been taken to enhancing the li
|
