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  • Taken together, these results demonstrate for the first time that IKK?? functions downstream of Akt2 to promote breast cancer cell survival.Keywords: IKK??, Akt2, NF-??B, TNF, breast cancerIntroductionThe transcription factor nuclear factor-??B (NF-??B) is an important regulator of critical cellular processes such as cell growth, proliferation, and survival.1-3 Aberration in NF-??B???associated pa
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