| http://www.w3.org/ns/prov#value | - Agent: 20120142656 - Buccal application system comprising 17a-estradiol: The invention relates to application systems for buccal application, comprising 17??-estradiol in a dosage of 50 to 400 ??g, preferably 200 to 400 ??g, particularly preferably 300 ??g, together with one or more pharmaceutically acceptable additives or media for implementing the treatment or minimization of hot flashes in wome
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