| http://www.w3.org/ns/prov#value | - These data suggest that IL-12 is specialized in stimulating macrophages to release IFN-??, whereas IFN-?? is able to activate many functional activities of macrophages.IL-18 (IFN-?????inducing factor), a recently identified cytokine, can be released from macrophages and structural tissue cell types and has been shown to synergize with IL-12 to induce IFN-?? from Th1 and NK cells (4).
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