| http://www.w3.org/ns/prov#value | - As large amounts of negative charges are conferred by adding extensive polymers of ADP-ribose (PAR), PARP1 modulates the activity of its substrates, including itself, to control several important cellular functions (Figure 1) such as DNA damage repair, transcriptional regulation and cell death [6,16,19,20,21,22,31,36,37,38,39,40,41,42].
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