| http://www.w3.org/ns/prov#value | - Recent studies have identified specific miRNAs that regulate the cell cycle and documented that the loss or gain of miRNA-mediated cell-cycle control contributes to malignancy. miRNAs regulate classic cell-cycle control pathways by directly targeting proteins such as E2F transcription factors, cyclin-dependent kinases (Cdks), cyclins, and Cdk inhibitors (CKIs).
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