| http://www.w3.org/ns/prov#value | - The Hydroxyiminopiperazine Compounds wherein R4 is ???C(O)NHR9 can be obtained by reacting a Hydroxyiminopiperazine Compound wherein R4 is ???H with an isocyanate, R9???N???C???O, in a suitable solvent, fore example toluene, at a suitable temperature, for example at reflux temperature, to provide the Hydroxyiminopiperazine Compound wherein R4 is ???C(O)NHR9 as shown below in Scheme E:
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