| http://www.w3.org/ns/prov#value | - More particularly, the present invention relates to a composition comprising an antiandrogenic tricyclic compound of formula 1 ##STR2## wherein R is COR1 wherein R1 is loweralkyl and a vehicle comprising a metabolism modulator and a polar organic solvent, and a method of controlling permeation and metabolism of the tricyclic compound thereof in mammalian skin, mucosa, and other membrane tissue.
|
