| http://www.w3.org/ns/prov#value | - Immunomodulatory Strategies The autoantigenic enzyme tissue transglutaminase (TTG) is mainly expressed in the lamina propria, and its expression is upregulated by various stimuli, such as mechanical stress or bacterial/viral infection, during active CD. The enzyme catalyzes transamidation between a glutamine residue of a glutamine-donor protein and a lysine residue of a glutamine-acceptor protein,
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