| http://www.w3.org/ns/prov#value | - This mode of regulation ensures that in response to cellular stresses such as endoplasmic reticulum stress, cells are capable of quickly activating a pool of Nrf2, leading to gene expression patterns that counteract the toxic effects brought on by the stress.If Keap1 can prevent Nrf2 nuclear entry, is Cul3-dependent proteolysis an essential regulatory component?
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