| http://www.w3.org/ns/prov#value | - As explained in the text, NEP expression and activity in brain cortex and hippocampus (the structures which are characterised by accumulation of amyloid deposits) decreases with age and is also decreased after prenatal hypoxia, ischemia, or in the case of AD. In animal models, NEP activity can be modulated by its inhibitors affecting such brain functions as learning and memory.
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