| http://www.w3.org/ns/prov#value | - NO is a gaseous molecule able to regulate vasodilatation, shear stress and vascular tone and to prevent thrombotic events and vascular inflammation [55].The production of ROS increases during ageing and determines oxidative stress, which might be responsible for the SIRT1, a class III histone deacetylases, decreased activity and protein levels [56].
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