| http://www.w3.org/ns/prov#value | - It is a key downstream effector of phosphoinositide 3-kinase (PI3K) and sends signals to a wide range of apoptotic and metabolic regulators including GSK3, FOXO and TSC2.1 Because the PI3K/Akt signaling pathway is dysregulated in a number of human diseases such as cancer and diabetes, modulation of the pathway is a significant therapeutic goal.
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