| http://www.w3.org/ns/prov#value | - The expression of scavenger receptors is regulated by peroxisome proliferator-activated receptor-??, a transcription factor whose ligands include oxidized fatty acids, and by cytokines such as tumour necrosis factor-?? and interferon-?? (IFN-??)29.Macrophages actively secrete apoE, and this may promote cholesterol efflux to HDL, thereby inhibiting the transformation of macrophages to foam cells.
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