| http://www.w3.org/ns/prov#value | - These siRNAs are aimed at silencing single specific mRNA targets, but may have off-target side-effects (Jackson et al., 2003). miRNAs such as mir-296, however, can regulate a broad range of ???natural??? mRNA targets (Miranda et al., 2006) and therefore might prove more efficient for fine-tuning cellular switch programs.
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