| http://www.w3.org/ns/prov#value | - AMD3100 is a rapid mobilizing agent that is administrated only once.10 This agent enhances CXCR4-dependent HSPC recruitment to the circulation by triggering SDF-1 secretion from BM CXCR4+ stromal cells followed by its release from the BM to the circulation, leading to urokinase plasminogen activator (uPA), MMP-9, and reactive oxygen species (ROS) activation.13,25??????27
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