| http://www.w3.org/ns/prov#value | - The most frequently mutated of these genes is BRAF, with substitution of glutamic acid for valine at position V600 being the most common mutation [57].Vemurafenib is an oral selective inhibitor of oncogenic V600E mutant BRAF. It is indicated as monotherapy for the treatment of V600E mutation-positive unresectable or metastatic melanoma.
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