| http://www.w3.org/ns/prov#value | - TNF-a is a proinflammatory cytokine produced by monocytes, T lymphocytes, macrophages, and fibroblasts that stimulates prostaglandin E2 (PGE2) and collagenase release from human synovial cells10 and potentiates osteoclast differentiation (osteoclastogenesis) and activation11.
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