| http://www.w3.org/ns/prov#value | - After the functional rearrangement of heavy and light chain immunoglobulin genes during the progenitor (pro-B) and precursor (pre-B) cell stages in differentiation, naive B cells selected for nonself reactivity migrate from bone marrow to colonize the peripheral lymphoid tissues, including the spleen, lymph nodes, tonsils, intestinal Peyer's patches, and appendix (for reviews see references 3, 4).
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