| http://www.w3.org/ns/prov#value | - The murine sequence still specifically inhibited the hamster PrP conversion reaction with an excellent IC50 of 70 ??M. The hamster P113-136 sequence is conserved across both species (and indeed across multiple species such as human, mouse, hamster, cow and sheep), demonstrating that mutations outside this sequence are not deleterious to the specific inhibition reaction.
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