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  • However, many side effects have been described such as thrombotic effects and hypertension. we therefore synthesized new compounds and evaluation of their inhibition on vegfr-2 is under investigation. these molecules have been built from heterocycles such as 3-aminoselenophenes, 3-amino and 2-aminothiophenes, 4-aminothiazoles and selenazoles to give different polycyclic containing pyrimidinone, py
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