| http://www.w3.org/ns/prov#value | - As a proinflammatory mediator, OPN plays a role in the progression of chronic inflammatory and autoimmune diseases through various mechanisms, including involving in generation of Th1 and Th17 cells that are pathogenic T cells for various inflammatory diseases [22???24], inhibiting apoptosis of autoreactive immune cells and recruitment of leukocytes to sites of inflammation [21, 25].Recently, the
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