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  • In addition to risk factors such as diabetes and hypertension, genetic factors may also play a role in the development of these retinal microvascular signs [4,5].Transcription factor 7-like 2 (TCF7L2), a Wingless and Int (Wnt) signaling-associated transcription factor located on chromosome 10q25, has emerged as a consistently replicated susceptibility gene for type 2 diabetes [6-8], possibly throu
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  • pubmedcentralcanada.ca