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  • Earlier studies using creatine with HD mouse models as well as smaller pilot clinical trials led by Drs. Hersch and Rosas demonstrated impressive results.???Large amounts of creatine have to be ingested in order for therapeutic levels to reach the brain, so safety was a big concern,??? says Dr. Hersch. ???However, our Phase II trial with only 10 patients showed that high levels were safe and reach
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  • massgeneral.org