| http://www.w3.org/ns/prov#value | - Among its contributions to host defense, TNF-?? concentrates antimycobacterials in macrophages.128In a murine model, it enhanced the antibacterial activity of clofazimine against MAC.129 Overproduction of TNF-?? is believed to have systemic effects including fever production, weight loss, and tissue necrosis.121
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