| http://www.w3.org/ns/prov#value | - When using tobacco products, nicotine rapidly distributes from the lungs to the brain [13,14] where it interacts with high-affinity nicotinic acetylcholine receptors (nAChRs), resulting in rapid, pulsatile increases in the release of several neurotransmitters, notably dopamine in the mesolimbic system [15,16].
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